#4 Amidst challenging conditions consisting of heavy rain, wind gusts of more than 25 miles per hour, and some of the coldest temperatures in 30 years, Desiree "Desi" Linden, 34 and two-time Olympian, won the 122nd Boston Marathon and became the first American woman to win the women's race since Lisa Larsen Weidenback did so in 1985 after pulling away from a competitive field.  Watch her winning moment here.